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. 2001 Nov 21;70(1):181–191. doi: 10.1086/338308

Table 10.

Estimated Sample Sizes for Three Affected Siblings under Single-Locus Models^[Note]

	Estimated Sample Size
	Dominant Model				Additive Model				Recessive Model
Pedigree and Statistic(s)	1	2	3	4	5	6	7	8	9	10	11	12
Three males:
All statistics	11	11	11	22	11	11	11	22	11	11	11	22
Two males–one female:
Optimal test	13	14	14	28	13	13	14	32	11	12	14	48
S_all	13	14	14	28	13	14	14	32	11	12	14	54
S_X75	13	14	14	28	13	13	14	32	11	12	14	56
S^A_pairs	13	14	14	29	13	14	14	34	11	12	14	64
S_X50, S^GH_pairs	14	14	15	29	13	14	15	33	12	13	14	50
One male–two females:
Optimal test	20	21	22	52	24	25	26	72	11	11	12	46
S_all, S_X75	21	22	23	54	24	25	26	72	11	11	12	47
S^A_pairs, S_X50	20	21	22	52	24	25	27	74	11	11	12	46
S^GH_pairs	22	23	24	56	24	26	27	73	11	12	12	49
Three females:
All statistics	220	224	227	309	237	243	248	429	11	11	11	34

Note.— Notation is as described in the footnotes to table 9.