Echocardiographic data shows improvement after injection of myocardial matrix. (A) Ejection fraction (EF), end-diastolic volume (EDV), and end-systolic volume (ESV) are shown for each animal pre-MI, pre-injection (2 weeks post-MI), and pre-euthanasia for both the control (n = 4) and matrix-injected (n = 6) groups. Control animals that received saline injections are indicated with open circles (green and blue lines); animals that received no injection are represented with open triangles (red and purple lines). (B) Comparison of the absolute changes in EF, EDV, and ESV from either pre-MI baseline or pre-injection to the time of euthanasia. (C) Global wall motion index improves in matrix-treated animals. Note that error bars are present but not visible for the matrix-injected group at pre-euthanasia. All data are means +/− SEM. *p < 0.05 versus control (Student’s t-test).