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. Author manuscript; available in PMC: 2013 Dec 3.
Published in final edited form as: Behav Brain Res. 2012 Jan 8;229(1):160–167. doi: 10.1016/j.bbr.2012.01.001

FIGURE 1. Time course of CFA-induced inflammatory pain behavior.

FIGURE 1

Changes in withdrawal thresholds to mechanical stimulation with the dynamic von Frey filament were assessed on both (A) ipsilateral and (B) contralateral hind paws of CFA and control groups, at day 0 (BL), and days 7, 14, 21, and 28 post-CFA injection. All data represent means ± S.E.M. (n = 12 for the control group and n = 11 for the CFA group). Statistical analyses were performed using a 2-way ANOVA followed by the Bonferroni post-hoc test. Asterisks denote a significant difference from saline-injected animals; ***P < 0.001.