Table 2. Morphological parameters of the pulmonary system used in the model.
Parameter | Value | Reference |
Total lung volume | 1.43 ml | Measured in mice by [43] |
Total lung mass | 0.43 g | Measured in mice by [43] |
Volume of alveolar fluid | 10 ml/kg BW | Reported in sheep by [44] |
Alveolar surface | 0.0082 m2 | For 0.3 ml lung [45] |
Thickness of alveolar interface | 0.2 m | Reported in rats by [46] |
Volume of single Type II cell | 385.7 m3 | Number weighted mean in rats [47] |
No. of Type II cells | 9.13×107 per g lung | Reported in mice by [13] |
No. of alveolar macrophages | 1.66×105 | Reported in mice by [48] |
Volume of LB per Type II cell | 61.3 m3 | Reported in rats by [47] |
No. of LB per Type II cell | 150 | Estimated in rats by [49] |