Table 2.
Baseline clinical and viro-immunological characteristics of 67 HIV-infected naive pregnant women with valuable results from the HIV genotypic drug-resistance assay
|
Characteristics |
HIV-infected pregnant women with a valuable result at HIV genotype n° 67 |
p value |
|
|---|---|---|---|
| Women with wild-type genotype n° 59 | Women with any drug-resistant mutation n°8 | ||
| Age, years, mean ± SD |
28.6 ± 5.3 |
30.6 ± 4.7 |
0.3 |
| Gestational age at enrolment, week, mean ± SD; |
20.8 ± 4.9 |
17.2 ± 4.4 |
0.06 |
| Height at screening, cm, mean ± SD |
155.9 ± 5.9 |
155.3 ± 3.2 |
0.8 |
| Race/ethnicity, |
|
|
|
| Black African, n. (%) |
59 (100) |
8 (100) |
1 |
| Education, n. (%) |
|
|
0.3 |
| Primary school |
36 (61) |
7 (87.5) |
|
| Secondary school |
10 (16.9) |
1 (12.5) |
|
| Other or unknown |
13 (22) |
0 (0) |
|
| Number of pregnancies, mean ± SD |
2.9 ±1.5 |
2.6 ±1.8 |
0.6 |
| Number of deliveries, mean ± SD |
1.8 ±1.5 |
1.6 ±1.8 |
0.7 |
| Number of children, mean ± SD |
1.4 ±1.2 |
1.6 ±1.8 |
0.6 |
| HIV risk factor, n° (%) |
|
|
|
| Unprotected heterosexual relationship |
59 (100) |
8 (100) |
1 |
| WHO stage, n° (%) |
|
|
0.9 |
| 1 |
35 (59) |
4 (50) |
|
| 2 |
15 (25) |
3 (37.5) |
|
| 3 |
8 (14) |
1 (12.5) |
|
| 4 |
1 (2) |
0 |
|
| MedianCD4+ cells at enrolment /μL (IQR) |
406 (297-530) |
396 (240-461) |
0.7 |
| Days since HIV diagnosis, mean ± SD |
102 ±182 |
117 ±28 |
0.8 |
| Median log10 HIV RNA copies/mL (IQR) |
9.28 (4.82-10.71) |
7.94 (3.58-9.49) |
0.3 |
| Eligible for HAART, n (%) |
9 (15.5) |
2 (25) |
0.5 |
| Positive VDRL assay, n (%) | 1 (1.9) | 1 (12.5) | 0.1 |
Note. Demographic, clinical and viro-immunological data were analyzed with Chi- square test and univariate analysis (significant level was set at 0.05).