Table 2. Local functions of various cytokine-mediated therapy.

Cytokine	Local Function
G-CSF	Stimulation of myeloid progenitor cells Mobilization of hemopoietic stem cells Healing and repair
EPO	Erythrocyte survival and differentiation Vascular auto regulation Prevention of apoptosis and inflammation
SDF-1	Stimulates hematopoietic and endothelial progenitors Activates mesenchymal stem cells Neovascularization
TNF-α	Downregulate myocyte contractility
IL-6	Reduction of systolic cytosolic [Ca2+]