Table 1.
Data type | Metegnome sequencing | 16S rRNA | |||
---|---|---|---|---|---|
Feature type |
Alignment-free |
Alignment-based |
OTU-based or microbial taxon-based |
||
(based on sequence signature features without using any database) |
(based on features obtained by mapping sequence reads to annotation databases) |
||||
Type of machine learning | Supervised classification | Unsupervised clustering | Supervised classification | Unsupervised clustering | Supervised or unsupervised |
The highlighted category (alignment-free supervised classification of metagenome data) is that of the current work.