Table 2. Correlation between Notch1 expression and clinicopathological features in patients with colorectal cancer.
Notch1 Expression | ||||
Characteristic | Number | Negative | Positive | P |
Age | 0.311 | |||
≤60 | 233 | 95 (40.8) | 138 (59.2) | |
>60 | 216 | 94 (43.5) | 122 (56.5) | |
Sex | 0.163 | |||
male | 248 | 110 (44.4) | 138 (55.6) | |
female | 201 | 79 (39.3) | 122 (60.7) | |
LNM | 0.067 | |||
negative | 256 | 116 (45.3) | 140 (54.7) | |
positive | 193 | 73 (37.8) | 120 (62.2) | |
TNM stage | 0.024 | |||
I | 84 | 35 (41.7) | 49 (58.3) | |
II | 165 | 83 (50.3) | 82 (49.7) | |
III | 145 | 55 (37.9) | 90 (62.1) | |
IV | 55 | 16 (29.1) | 39 (70.9) | |
Infiltrate depth | 0.018 | |||
T1+T2 | 234 | 110 (47.0) | 124 (53.0) | |
T3+T4 | 215 | 79 (36.7) | 136 (63.3) | |
Differentiation | 0.007 | |||
well | 159 | 81 (50.9) | 78 (49.1) | |
moderately | 194 | 78 (40.2) | 116 (59.8) | |
poorly | 96 | 30 (31.2) | 66 (68.8) | |
Tumor location | 0.408 | |||
rectum | 206 | 85 (41.3) | 121 (58.7) | |
colon | 243 | 104(42.8) | 139(57.2) |
LNM, Lymph node metastasis; TNM, tumor node metastasis.