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. 2013 Dec 3;8(12):e81005. doi: 10.1371/journal.pone.0081005

Table 2. Correlation between Notch1 expression and clinicopathological features in patients with colorectal cancer.

Notch1 Expression
Characteristic Number Negative Positive P
Age 0.311
≤60 233 95 (40.8) 138 (59.2)
>60 216 94 (43.5) 122 (56.5)
Sex 0.163
male 248 110 (44.4) 138 (55.6)
female 201 79 (39.3) 122 (60.7)
LNM 0.067
negative 256 116 (45.3) 140 (54.7)
positive 193 73 (37.8) 120 (62.2)
TNM stage 0.024
I 84 35 (41.7) 49 (58.3)
II 165 83 (50.3) 82 (49.7)
III 145 55 (37.9) 90 (62.1)
IV 55 16 (29.1) 39 (70.9)
Infiltrate depth 0.018
T1+T2 234 110 (47.0) 124 (53.0)
T3+T4 215 79 (36.7) 136 (63.3)
Differentiation 0.007
well 159 81 (50.9) 78 (49.1)
moderately 194 78 (40.2) 116 (59.8)
poorly 96 30 (31.2) 66 (68.8)
Tumor location 0.408
rectum 206 85 (41.3) 121 (58.7)
colon 243 104(42.8) 139(57.2)

LNM, Lymph node metastasis; TNM, tumor node metastasis.