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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2013 Sep 26;1841(1):10.1016/j.bbalip.2013.09.010. doi: 10.1016/j.bbalip.2013.09.010

Fig. 5.

Fig. 5

Lung relative weight, cholesterol content, rates of cholesterol and fatty acid synthesis and histology in Npc2+/+ and Npc2−/− mice at 70 days of age. (A–D) the organ weight and metabolic data were obtained from a single study using six Npc2+/+ and six Npc2−/−, all at 70 days of age. For all of these parameters the values are mean ± 1 SEM. The asterisk denotes a statistically significant difference (p<0.05). Separate mice were used to obtain lungs for histology. The two lower images show representative histological sections of lung tissue in Npc2+/+ (E) and Npc2−/− (F) mice. The arrow points to a lipid-laden macrophage within the alveoli of the Npc2−/− mouse. The scale bar equals 100µm (E) and both images are at the same magnification (×400).