Figure 3. Genomic context and associated coding-genes for the identified lncRNAs. (A) AK087060 originates 200 bps downstream from the transcription start site of the mRNA for the Arhgef26 gene. Genomic organization of the human gene is also shown (ARHGEF26). (B) Upregulation of AK087060 in Mecp2 KO mice is associated with an increase in the expression levels of the host gene in the four studied brain regions (Pearson's correlation test = 0.41, p = 0.08). (C) AK081227 is transcribed from the last intron of the Gabrr2 gene. Genomic organization of the human gene is also shown (GABRR2). (D) Upregulation of AK087060 in Mecp2 KO mice is associated with a downregulation in the expression levels of the host gene in the four studied brain regions (Pearson's correlation test = 0.44, p = 0.06). Orange dots, frontal cortex; green dots, thalamus; blue dots, hipothalamus; red dots, cerebellum.