. 2013 Sep 26;13:212. doi: 10.1186/1471-2180-13-212

Table 1.

MIC data for lacticin 3147, polymyxin B and polymyxin E alone and in combination

Organism	MIC (μg/ml)
	Lacticin 3147	Polymyxin B	Polymyxin E	Lacticin 3147/	FIC	Lacticin 3147/	FIC
				Polymyxin B		Polymyxin E
Salmonella Typhimurium UK1	924	0.0586	0.0586	924/0.015	1.25^d	924/0.0073	1.125^d
Salmonella Typhimurium LT2	231	0.3125	0.4688	No MIC	>4^e	No MIC	>4^e
Cronobacter sakazakii DPC 6440	>924	0.3125	0.3125	57.75/0.0781	0.250 (<0.312)*^a	57.75/0.0195	0.062 (<0.125)*^a
E. coli 0157:H-	231	0.0586	0.0781	28.875/0.0073	0.250^a	28.875/0.0049	0.188^a
E. coli DH5α	462	0.0781	0.0781	28.875/.0098	0.188^a	28.875/0.0098	0.188^a
E. coli EC101	462	0.0781	0.0781	14.4375/.0391	0.5^a	28.875/0.0098	0.188^a
E. faecium DO	0.9625	>375	>375	0.9625/23.4375	1^c	0.9652/23.4375	1^c
B. cereus 8079	3.85	187.5	375	1.925/23.4375	0.62^b	3.85/375	2^d
S .aureus 5247	15.4	187.5	>375	7.7/46.875	0.75^b	15.4/23.4375	1^c

FIC figures have been calculated as a result of triplicate experiments and indicate ^asynergy, ^bfor partial synergy, ^cadditive effects, ^dindifference, and ^eantagonism between the combined antimicrobials. *FIC index which includes the reduction in lacticin 3147 MIC from the highest level tested to that which achieves an MIC in the presence of polymyxin.