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. 2013 Sep 23;10:102. doi: 10.1186/1742-4690-10-102

Table 1.

Individual’s data summary

Individual Geometric mean IC50 titera Number of viruses neutralizedb Date of SCc Months from SC to CVId CD4 count at SPe Viral load (log) at SPf Env sequences obtainedg Neutralization assay performedh SH analysis performedi
ACH19829
 297
 6
 26-jan-86
 10.5
 440
 3.9
 gp160
 +
 +
ACH18969
 275
 5
 29-Oct-87
 1.8
 520
 4.3
 gp160
 +
 +
ACH19308
 231
 5
 14-jul-91
 3.3
 380
 4.4
 gp160
 +
 +
ACH18814
 230
 6
 27-jul-87
 3.2
 500
 5.1
 gp160
 +
 +
ACH18818
 205
 4
 26-jan-86
 8.2
 510
 5.4
 gp160
 +
 +
ACH19885
 180
 5
 28-dec-94
 2.9
 580
 3.3
 gp160
 +
 +
ACH11668
 169
 5
 28-jun-86
 7.9
 380
 4.5
 gp160
 +
 +
ACH19463
 164
 5
 14-jul-86
 2.1
 350
 4.8
 gp160
 +
 +
ACH19507
 140
 6
 23-apr-88
 7.9
 400
 5.0
 gp160
 +
 +
ACH19474
 126
 5
 27-jul-87
 12.7
 410
 3.0
 gp160
 +
 +
ACH19999
 111
 4
 26-aug-85
 4.3
 1060
 4.6
 gp160
 +
 +
ACH19793
 93
 4
 28-jun-86
 12.3
 1000
 4.5
 gp160
 +
 +
ACH19588
 91
 4
 20-nov-85
 13.8
 600
 5.3
 gp160
 -
 -
ACH19566
 78
 5
 11-Mar-85
 13.2
 610
 3.5
 C1-V5
 -
 -
ACH19768
 64
 5
 6-apr-86
 2.2
 370
 3.7
 gp160
 -
 -
ACH18860
 64
 2
 25-aug-86
 2.6
 550
 4.9
 C1-V5
 -
 -
ACH18839
 64
 3
 17-Oct-86
 3.3
 330
 3.8
 C1-V5
 -
 -
ACH19542
 45
 3
 23-jun-85
 4.5
 310
 3.9
 gp160
 -
 -
ACH18766
 43
 1
 15-jul-88
 5.1
 760
 4.3
 gp160
 -
 -
ACH19861
 43
 3
 24-feb-89
 3.0
 470
 4.3
 gp160
 +
 +
ACH19453
 39
 3
 23-dec-85
 7.0
 810
 3.0
 gp160
 -
 -
ACH18829
 38
 3
 2-feb-87
 4.0
 770
 2.6
 C1-V5
 -
 -
ACH19792
 34
 2
 8-nov-85
 6.9
 450
 4.9
 gp160
 +
 +
ACH19961
 31
 0
 14-sep-87
 2.4
 530
 4.5
 gp160
 +
 +
ACH19329
 31
 1
 28-dec-94
 4.3
 780
 3.9
 gp160
 +
 +
ACH19974
 29
 2
 26-jan-86
 8.8
 550
 3.5
 gp160
 +
 +
ACH19489
 29
 0
 30-sep-85
 7.4
 550
 3.1
 gp160
 +
 +
ACH18887
 29
 1
 7-dec-89
 8.8
 670
 4.6
 gp160
 +
 +
ACH19342
 28
 2
 14-jul-86
 3.0
 700
 3.9
 C1-V5
 -
 -
ACH19576
 23
 1
 2-feb-88
 7.0
 500
 4.5
 gp160
 +
 +
ACH18880 20 0 28-jun-86 10.4 860 4.8 gp160 + +

aNeutralization titers are expressed as the geometric mean of the reciprocal plasma dilution that inhibited virus infection by 50% for the panel of 6 heterologous viruses.

bThe number of viruses neutralized, at least 3-fold higher than the IC50 of the same serum with MLV, from the panel of 6 heterologous viruses from different subtypes.

cDate of seroconversion (SC).

dMonths post SC to time of clonal virus isolation (CVI).

eCD4+ T-cell (CD4+) count at setpoint (SP).

fLog viral load at setpoint (SP).

gEnv fragment sequenced.

hIndividuals from which viruses were used in the neutralization sensitivity assay with MAbs and polyclonal HIVIg pools are indicated with +.

IIndividuals from which viral sequences were used in the Sequence Harmony model are indicated with +.