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. Author manuscript; available in PMC: 2013 Dec 3.
Published in final edited form as: Proteins. 2011 Nov 17;80(2):490–504. doi: 10.1002/prot.23215

Figure 6.

Figure 6

Performance of a simple optimiser using different fragment lengths L and move sizes M as a function of noise for (a) F = 5 and (b) F = 25. We mainly consider settings where L = M (as used in standard Rosetta), but the graph for L = 18, M = 3 is used to illustrate an additional effect of search space size. Performance is assessed using the mean number of iterations required to identify a solution with MSE (≤ 9, over 100 runs). The results demonstrate clearly that optimal move size decreases, as noise levels increase. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]