Table 1.
Baseline characteristics of HD patients
|
HD patients |
ESA ≤8,000 (units/week) |
ESA >8,000 (units/week) |
||
|---|---|---|---|---|
| |
Hb ≥11 (g/dl) |
Hb <11 (g/dl) |
Hb ≥11 (g/dl) |
Hb <11 (g/dl) |
| Number | 380 | 264 | 158 | 211 |
| Age (years) |
64.5 (13.2) |
64.1 (14.4) |
64.9 (13.7) |
64.2 (12.8) |
| Sex (%) men |
60.4 |
56.1 |
65.0 |
56.4 |
| Weight (kg) |
70.6 (12.4) |
72.0 (14.3) |
74.1 (14.9) |
73.6 (14.8) |
| ESA dose (units/week) |
6,000 (4,000-8,000) |
6,000 (4,000-8,000) |
12,000 (10,000-16,000) |
12,000 (12,000-18,000) |
| ERI (units/week/kg/Hb) |
6.5 (2.9) |
7.9 (3.4) |
16.0 (6.3) |
22.3 (13.5) |
| Primary kidney disease (%) |
|
|
|
|
| - Diabetes mellitus |
10.6 |
17.4 |
16.5 |
15.6 |
| - Glomerulonephritis |
11.1 |
7.6 |
8.2 |
8.5 |
| - Renal vascular disease |
22.2 |
21.6 |
12.7 |
19.0 |
| - Other |
56.2 |
53.4 |
62.7 |
56.9 |
| Comorbidity (%) |
|
|
|
|
| - Diabetes mellitus |
17.1 |
20.8 |
27.2 |
24.2 |
| - Malignancy |
7.4 |
9.8 |
11.4 |
18.5 |
| - Cardiovascular disease |
39.2 |
41.3 |
32.9 |
40.8 |
| Weekly Kt/V urea (Watson) |
3.7 (0.9) |
3.5 (0.9) |
3.7 (0.8) |
3.7 (1.0) |
| rGFR (ml/min/1.73 m2) |
2.9 (1.5-4.4) |
2.3 (0.8-3.8) |
2.1 (0.8-4.2) |
1.5 (0.4-3.2) |
| Nutritional status (SGA) (%) |
|
|
|
|
| - Severely malnourished |
0.3 |
2.2 |
0.8 |
5.4 |
| - Mild-moderate |
19.1 |
25.4 |
27.1 |
37.3 |
| - Well-nourished |
80.6 |
72.4 |
72.0 |
57.2 |
| Laboratory values |
|
|
|
|
| - Hemoglobin (g/dl) |
12.1 (11.6-12.7) |
10.3 (9.5-10.6) |
12.1 (11.6-12.8) |
9.8 (9.2-10.5) |
| - Albumin (g/l) |
37.5 (4.5) |
36.0 (4.9) |
35.6 (4.5) |
34.1 (6.0) |
| - Ferritin (μg/l) |
190 (104–380) |
175 (94–379) |
229 (121–434) |
257 (118–511) |
| - PTH (pmol/l) |
12.1 (5.5-23.8) |
10.6 (4.7-23.9) |
16.3 (6.4-33.7) |
10.0 (3.2-23.4) |
| - CRP (mg/l) | 6.0 (3.0-12.0) | 6.0 (3.0-15.0) | 9.0 (3.0-17.0) | 14.0 (6.0-34.5) |
Values are presented as mean (SD), median (IQR) or percentage.