Table II.
Demographic information of control, MCI, and AD subjects used for the identification of proteins with altered protein levels.
| Controls | MCI | AD | |
|---|---|---|---|
| n. | 5 | 5 | 5 |
| M/F | 1/4 | 5/0 | 0/5 |
| age | 76.6 ± 7.4 | 79.6 ± 7.5 | 82.6 ± 4.6 |
| MMSE | 29.0 ± 1.4 | 24.8 ± 1.1 | 18.8 ± 2.4 |
| ACE-R | 87.6 ± 7.6 | 71.4 ± 9.9 | 44.2 ± 9.9 |
| GDS | 3.8 ± 1.3 | 4.4 ± 1.1 | 5.2 ± 2.3 |
| HIS | 2.0 ± 1.4 | 3.0 ± 2.9 | 2.6 ± 1.1 |
| ADL | 5.2 ± 0.4 | 5.4 ± 0.5 | 4.8 ± 1.3 |
| IADL | 6.0 ± 1.9 | 4.4 ± 0.5 | 2.0 ± 1.2 |
*
p< 0.001 for MMSE, ACE-R and IADL among groups (Kruskal Wallis test)
MMSE Mini Mental State Examination (range 0–30)
ACE-R Addenbrooke’s Cognitive Examination-Revised (range 0–100)
GDS Geriatric Depression Scale (range 0–15)
HIS Hachinski Ischemic Score (range 0–18)
ADL Activity of Daily Living (range 0–6)
IADL Instrumental Activity of Daily Living (range 0–8)