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. 2013 Sep 22;12:106. doi: 10.1186/1476-4598-12-106

Table 3.

Comparison in gene expression level between ER positive and negative tumors

Gene symbol Gene title Fold changea Adjusted
P-valueb
ANO1
anoctamin 1, calcium activated chloride channel
2.09
< 0.001
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
0.65
0.043
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
5.59
< 0.001
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
1.30
0.033
CACNA2D2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
2.61
< 0.001
CLCA2
chloride channel accessory 2
0.46
0.017
CLIC4
chloride intracellular channel 4
0.75
0.008
CLIC6
chloride intracellular channel 6
5.86
< 0.001
GABRP
gamma-aminobutyric acid (GABA) A receptor, pi
0.20
0.020
GLRB
glycine receptor, beta
3.42
< 0.001
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
0.72
0.013
KCND3
potassium voltage-gated channel, Shal-related subfamily, member 3
2.36
< 0.001
KCNE3
potassium voltage-gated channel, Isk-related family, member 3
0.75
0.003
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
12.64
< 0.001
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
6.22
< 0.001
KCNK6
potassium channel, subfamily K, member 6
1.82
< 0.001
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
1.45
0.035
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
0.42
< 0.001
KCNS3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
1.58
0.028
MCOLN2
mucolipin 2
0.46
0.002
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
1.82
< 0.001
SCN7A
sodium channel, voltage-gated, type VII, alpha subunit
1.71
0.009
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
2.00
< 0.001
TPCN1 two pore segment channel 1 1.38 < 0.001

aFold change is calculated by dividing the mean expression of ER positive tumor by the mean expression of ER negative tumor.

bP-value is calculated by two-tailed t-test and adjusted by Benjamini & Hochberg correction.