Table 4.
Correlation between gene expression and histological tumor grade
| Gene symbol | Gene title | ρa |
Adjusted |
|---|---|---|---|
| P-valueb | |||
|
ANO1 |
anoctamin 1, calcium activated chloride channel |
-0.23 |
< 0.001 |
|
CACNA1D |
calcium channel, voltage-dependent, L type, alpha 1D subunit |
-0.42 |
< 0.001 |
|
CACNA2D1 |
calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
-0.28 |
< 0.001 |
|
CACNA2D2 |
calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
-0.30 |
< 0.001 |
|
CLIC1 |
chloride intracellular channel 1 |
0.26 |
< 0.001 |
|
CLIC4 |
chloride intracellular channel 4 |
0.16 |
0.022 |
|
CLIC5 |
chloride intracellular channel 5 |
-0.22 |
0.001 |
|
CLIC6 |
chloride intracellular channel 6 |
-0.33 |
< 0.001 |
|
GLRB |
glycine receptor, beta |
-0.35 |
< 0.001 |
|
KCNAB2 |
potassium voltage-gated channel, shaker-related subfamily, beta member 2 |
0.15 |
0.023 |
|
KCND3 |
potassium voltage-gated channel, Shal-related subfamily, member 3 |
-0.39 |
< 0.001 |
|
KCNE3 |
potassium voltage-gated channel, Isk-related family, member 3 |
0.23 |
< 0.001 |
|
KCNE4 |
potassium voltage-gated channel, Isk-related family, member 4 |
-0.38 |
< 0.001 |
|
KCNK1 |
potassium channel, subfamily K, member 1 |
0.25 |
< 0.001 |
|
KCNMA1 |
potassium large conductance calcium-activated channel, subfamily M, alpha member 1 |
-0.30 |
< 0.001 |
|
KCNN4 |
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 |
0.23 |
< 0.001 |
|
MCOLN2 |
mucolipin 2 |
0.25 |
< 0.001 |
|
P2RX4 |
purinergic receptor P2X, ligand-gated ion channel, 4 |
-0.24 |
< 0.001 |
|
PKD1 |
polycystic kidney disease 1 (autosomal dominant) |
-0.17 |
0.012 |
|
PKD2 |
polycystic kidney disease 2 (autosomal dominant) |
-0.19 |
0.004 |
|
SCN1B |
sodium channel, voltage-gated, type I, beta subunit |
-0.27 |
< 0.001 |
|
SCN7A |
sodium channel, voltage-gated, type VII, alpha subunit |
-0.41 |
< 0.001 |
|
SCNN1A |
sodium channel, non-voltage-gated 1 alpha subunit |
-0.18 |
0.008 |
|
TPCN1 |
two pore segment channel 1 |
-0.26 |
< 0.001 |
|
TPCN2 |
two pore segment channel 2 |
0.17 |
0.013 |
|
TRPC1 |
transient receptor potential cation channel, subfamily C, member 1 |
-0.25 |
< 0.001 |
|
TRPM4 |
transient receptor potential cation channel, subfamily M, member 4 |
-0.21 |
0.002 |
|
VDAC1 |
voltage-dependent anion channel 1 |
0.21 |
0.002 |
|
VDAC2 |
voltage-dependent anion channel 2 |
0.22 |
0.001 |
| VDAC3 | voltage-dependent anion channel 3 | 0.26 | < 0.001 |
aρ is the Spearman’s rank correlation coefficient.
bP-value is calculated by Spearman’s rank correlation test and adjusted by Benjamini & Hochberg correction.