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. 2013 Dec 3;8(12):e81586. doi: 10.1371/journal.pone.0081586

Figure 2. Antitumorigenic activity of peonidin-3-glucoside or cyaniding-3-glucoside in xenografted nude mice.

Figure 2

(A) Body weight of animals. (B) H&E staining for kidney, liver, and spleen. (C and D) Effects on tumor volume and tumor weight. Nude mice bearing MDA-MB-453 cells as xenografts were treated with control (saline), or group 1 (peonidin-3-glucoside (6 mg/kg/day)) or group 2 (cyaniding-3-glucoside (6 mg/kg/day)). Values are means ± SE (n = 10). *P<0.05. (E) H & E staining, expression of phospho-HER2 and Ki67. Control: saline; Group 1: peonidin-3-glucoside (6 mg/kg/day); group 2: cyaniding-3-glucoside (6 mg/kg/day).