Table 5.
Predictors for the development of reflux esophagitis in patients who are not taking PPIs
| |
Univariate |
Multivariate |
||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Male sex |
2.57 |
1.68–3.93 |
< 0.0001 |
2.22 |
1.25–3.92 |
0.006 |
| Alcohol drinking |
1.47 |
1.01–2.15 |
0.05 |
1.10 |
0.68–1.80 |
0.70 |
| Gastric atrophy (Open-type) |
0.54 |
0.31–0.93 |
0.03 |
0.57 |
0.32–1.03 |
0.06 |
| BMI (25≤) |
1.95 |
1.31–2.92 |
0.001 |
1.51 |
0.85–2.70 |
0.16 |
| WC * |
1.98 |
1.37–2.87 |
0.0003 |
1.04 |
0.56–1.94 |
0.89 |
| WHR ** | 1.70 | 1.09–2.66 | 0.02 | 1.57 | 0.92–2.67 | 0.10 |
PPI proton pump inhibitor, OR odds ratio, CI confidence interval, BMI body mass index, WC waist circumference, WHR waist-to-hip ratio.
* Large waist circumference is defined as 85 cm ≤ for males and 90 cm ≤ for females.
** Large waist-hip ratio is defined as ≥ 0.9 for males and ≥ 0.85 for females.