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. Author manuscript; available in PMC: 2014 Nov 28.
Published in final edited form as: J Control Release. 2013 Aug 23;172(1):10.1016/j.jconrel.2013.08.016. doi: 10.1016/j.jconrel.2013.08.016

Table 1.

Cytotoxicity levels (IC50) of rGel, cG-L and rG-L in various cancer cell lines (CT 26, LS174T, 9L and PC-3).

Samples CT 26a LS174Ta 9La PC-3a
rGel 1630 ± 510 5870 ± 1030 3100 ± 420 3430 ± 1140
cG-L 37.3 ± 15.7*** 123.1 ± 26.9*** 1062 ± 22.7*** 57.8 ± 23.4**
rG-L 79.1 ± 21.4*** 67.8 ± 13.7*** 61.3 ± 12.2*** 83.6 ± 28.3**
a

IC50 values are displayed as nM.

**

P < 0.001

***

P < 0.0001.

For all experiments, N=3. (rGel: recombinant gelonin, cG-L: gelonin-LMWP chemical conjugate, rG-L: recombinant gelonin-LMWP chimera)