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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Behav Brain Res. 2013 Oct 16;258:10.1016/j.bbr.2013.10.012. doi: 10.1016/j.bbr.2013.10.012

Figure 1. Measurement of PGI2 production in brain.

Figure 1

(A) Examples showing 6-Keto-PGF1α detected using HPLC, using a positive control (COX-1-10aa-PGIS positive cell lysate), non-transgenic mouse, and TG-Cp mouse brain tissue. (B) This figure demonstrates that CP-Tg mouse tissue exhibits enhanced conversion of arachidonic acid to PGI2 (n=3, for each group, p<0.05), compared with control.