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. 2008 Jun 11;28(24):6250–6257. doi: 10.1523/JNEUROSCI.5219-07.2008

Figure 1.

Figure 1.

Increased anxiety-related behavior in adult mice treated during development, but not adulthood, with WAY100635. A, B, Adult wild-type mice treated with the selective Htr1a antagonist WAY100635 from P13 to P34 (WAY100635) showed increased anxiety-related behavior when compared with saline-treated littermates (saline) in the open field (OF; saline, n = 29; WAY100635, n = 27; A) and novelty-suppressed feeding test (NSF; saline, n = 19; WAY100635, n = 18; B). C, D, Adult mice treated with the selective Htr1a antagonist WAY100635 from P60 to P81 did not display altered anxiety-related behavior when compared with saline-treated littermates in the open field (saline, n = 23; WAY100635, n = 24; C) or novelty-suppressed feeding test (saline, n = 14; WAY100635, n = 14; D). Error bars indicate mean ± SEM. *p < 0.05.