Figure 3.

Unaltered level of αCaMKII T286 phosphorylation in the hippocampus of adult Htr1a^KO mice. A, Representative bands from Western blot analysis of p-αCaMKII, total αCaMKII, and actin immunoreactivity in total hippocampal extracts of adult wild-type (WT) or Htr1a^KO (KO) mice after novel environment exposure. B, C, Quantification of p-αCaMKII (B) and total αCaMKII immunoreactivity (C) were similar in WT and KO mice. Data are expressed as a percentage of optical density (intensity units per square millimeter) versus WT; intensity of bands was normalized versus actin (WT, n = 10; KO, n = 9). Error bars indicate mean ± SEM.