Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Sep 16;10:99. doi: 10.1186/1742-4690-10-99

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Virnik et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Antibody response to replicating (A and B) and non-replicating (C and D) rubella vectors. (A) Macaque DCVV received a single dose of replicating vectors. Anti-Gag antibodies were detectable 2 weeks post immunization and they rose progressively by weeks 4 to 7. (B) Macaque V584 was primed three times with DNA vaccine, which elicited a good antibody response, and these titers rose substantially between 2 and 4 weeks after a single dose of live vectors. (C, D) Macaques CL6V and CL67 received three doses of non-replicating vectors. Antibodies were barely detectable after the first dose (5 weeks post immunization), but titers rose progressively after the second (4 weeks post immunization) and third doses (2 weeks post immunization), eventually reaching the same levels as a single dose of live vectors.