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. 2009 May 6;29(18):6022–6032. doi: 10.1523/JNEUROSCI.0627-09.2009

Figure 7.

Figure 7.

Activation of receptors with two nonconsecutive or one intact agonist binding site. The HC-Y190T and HC-W55T subunits were coexpressed at a 1:1 ratio resulting in eight different arrangements of subunits (top panel). All eight arrangements give rise to a single amplitude class with a mean current of 5.6 pA at −70 mV. Recordings were obtained in the presence of 2 or 10 mm ACh. Traces are shown at two different timescales. Open and burst duration histograms are shown.