Table 2.
Statistically Significant Differences in Eight SNPs among Patients with IgAN versus Control Subjects[Note]
|
Statistical Significance in Subjects with |
||||||||
| Stratified Comparison | SELE8 | SELE13 | SELL1 | SELL4 | SELL5 | SELL6 | SELL10 | SELL11 |
| χ2: | ||||||||
| Allele frequency | 10.686095 | 11.572843 | 12.354986 | 12.242864 | 11.007155 | 22.701719 | 14.379202 | 12.292278 |
| Genotype frequency | 11.704698 | 11.980555 | 19.773932 | 14.392873 | 13.899272 | 24.560263 | 18.609493 | 12.969646 |
| Major homozygotes/others | 6.244945 | 7.624198 | 3.961227 | 5.494191 | 4.530285 | 10.306812 | 6.018957 | 7.538820 |
| Minor homozygotes/others | 9.025162 | 8.026010 | 19.481165 | 12.982878 | 12.975893 | 22.013996 | 17.377607 | 9.470623 |
| P: | ||||||||
| Allele frequency | .001079 | .000669 | .000440 | .000467 | .000908 | .000002 | .000149 | .000455 |
| Genotype frequency | .002873 | .002503 | .000051 | .000749 | .000959 | .000005 | .000091 | .001526 |
| Major homozygotes/others | .012455 | .005759 | .046560 | .019080 | .033300 | .001325 | .014153 | .006038 |
| Minor homozygotes/others | .002663 | .004611 | .000010 | .000314 | .000316 | .000003 | .000031 | .002088 |
Note.— The χ2 test was used to evaluate possible associations between different genotypes, allele frequencies, or patients.