Table 2.
Coded allele frequencies for glucose and insulin SNPs, stratified by racial/ethnic group
| SNP | SNP location | Gene | GWAS phenotype | CA | NCA | European Americans | African Americans | Hispanics | American Indians | East Asians |
|---|---|---|---|---|---|---|---|---|---|---|
| rs11708067 |
intron |
ADCY5 |
glucose |
a |
g |
0.78 |
0.84 |
NG |
NG |
NG |
| rs560887 |
intron |
G6PC2 |
glucose |
c |
t |
0.71 |
0.93 |
0.86 |
0.92 |
NG |
| rs4607517 |
5’ region |
GCK |
glucose |
a |
g |
0.18 |
0.07 |
NG |
0.25 |
NG |
| rs780094 |
intron |
GCKR |
glucose and insulin |
c |
t |
0.59 |
0.81 |
0.67 |
0.28 |
0.45 |
| rs7944584 |
intron |
MADD |
glucose |
a |
t |
0.73 |
0.95 |
NG |
NG |
NG |
| rs10830963 |
intron |
MTNR1B |
glucose |
g |
c |
0.28 |
0.07 |
0.23 |
NG |
NG |
| rs11558471 |
3’ UTR |
SLC30A8 |
glucose |
a |
g |
0.68 |
0.91 |
NG |
NG |
NG |
| rs4506565 |
intron |
TCF7L2 |
glucose |
t |
a |
0.32 |
0.45 |
NG |
NG |
NG |
| rs7903146 |
intron |
TCF7L2 |
glucose |
t |
c |
0.29 |
0.28 |
0.24 |
0.12 |
0.05 |
| rs35767 | 5’ region | IGF1 | insulin | g | a | 0.84 | 0.55 | NG | NG | NG |
CA: coded allele; NCA: non-coded allele; NG: not genotyped; UTR: untranslated region.