Table 4.
Multivariate logistic regression analyses: heart rate variability indices (independent variables) categorized by tertiles and their respective odds ratios for the presence of peripheral arterial disease (dependent variable)
| Odd ratio* | 95%CI | P | |
|---|---|---|---|
|
Time domain indices | |||
|
SDNN day | |||
| 1st tertile |
6.08 |
1.24 - 29.90 |
0.026 |
| 2nd tertile |
0.80 |
0.20 - 3.90 |
0.784 |
| 3rd tertile |
1.0 |
- |
- |
|
SDNNi night | |||
| 1st tertile |
7.67 |
1.60 - 37.30 |
0.012 |
| 2nd tertile |
1.14 |
0.20 - 6.20 |
0.878 |
| 3rd tertile |
1.00 |
- |
- |
|
Frequency domain indices | |||
|
High Frequency | |||
| 1st tertile |
7.37 |
1.50 - 37.30 |
0.016 |
| 2nd tertile |
5.16 |
0.90 - 30.00 |
0.068 |
| 3rd tertile |
1.00 |
- |
- |
|
Low Frequency | |||
| 1st tertile |
6.17 |
1.10 - 35.10 |
0.040 |
| 2nd tertile |
4.00 |
0.70 - 24.40 |
0.129 |
| 3rd tertile |
1.00 |
- |
- |
|
High Frequency / Low Frequency Ratio | |||
| 1st tertile |
7.42 |
1.50 - 37.10 |
0.015 |
| 2nd tertile |
2.01 |
0.40 - 11.30 |
0.392 |
| 3rd tertile |
1,00 |
- |
- |
|
Tridimensional return map | |||
|
P1 night | |||
| 1st tertile |
2.67 |
0.60 - 11.80 |
0.195 |
| 2nd tertile |
0.73 |
0.10 – 4.10 |
0.720 |
| 3rd tertile |
1.00 |
- |
- |
|
P2 day | |||
| 1st tertile |
8.42 |
1.50 - 47.50 |
0.016 |
| 2nd tertile |
2.59 |
0.40 - 15.90 |
0.305 |
| 3rd tertile | 1.00 | - | - |
* the odds ratio was adjusted for diabetes duration, HbA1C, hypertension, serum triglycerides, and urinary albumin excretion in each model. SDNN= SD of the R-R intervals; SDNNi = mean of the SD of R-R intervals calculated in 5-min segment; P1 = index reflecting sympathetic modulation; P2 = index reflecting vagal modulation; upper index tertile (3rd) for each index was considered as the reference (OR = 1).