Table 3.
Deletions in Families with Autism[Note]
|
No. of Sibs (Diagnosis) |
||||
| Markerand Family | Sex of Parent with Deletion | With a Deletion | Without a Deletion | Deletion Size(kb) |
| D7S630: | ||||
| AU018 | Male | 2 (PDD) | 1 (unaffected) | 57 |
| D7S517: | ||||
| AU026 | Female | 1 (autism), 1 (PDD2) | 1 (unaffected) | >69 |
| AU044 | Male | 2 (autism), 1 (unaffected) | 0 | 183 |
| AU098 | Male | 1 (autism) | 1 (autism) | 96 |
| D8S264: | ||||
| AU025 | Female | 0 | 2 (autism) | <5.9 |
| AU058 | Female | 2 (autism) | 0 | 260–283a |
| AU113 | Female | 1 (autism) | 1 (PDD2), 1 (unaffected) | 252–266a |
| D8S272: | ||||
| AU002 | Male | 1 (autism), 1 (unaffected) | 1 (autism) | 192 |
| AU085 | Female | 3 (PDD2) | 0 | 192 |
| AU141 | Female | 2 (autism) | 0 | 192 |
| AU142 | Female | 1 (autism), 1 (PDD2) | 0 | 192 |
| UO2 | Female | 2 (autism), 2 (unaffected) | 1 (unaffected) | 192 |
Note.— Deletions were initially detected in DNA samples isolated directly from blood.
a
Sizes may not be correct, because of potential errors in the genomic DNA contig covering this region.