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Diagnostic performance of an end of fast proinsulin >22 pmol/L or equivalent across three nonoverlapping series of NIH patients evaluated with a supervised fast. These data represent 176 patients with insulin-producing tumors and 50 control subjects. (Proinsulin prior to 1995 was not directly measured; values obtained using the indirect proinsulin assay were converted to concentrations using a correlation analysis between the indirect and direct proinsulin assays.)
