Table 2.
Postoperative morbidity stratified by intensified neoadjuvant radiochemotherapy
| With neoadjuvant treatment% (n = 106) | Without neoadjuvant treatment% (n = 106) | p-value | |
|---|---|---|---|
| 30 day mortality |
0.0 |
1.9 |
0.244 |
| Complications |
53.8 |
50.5 |
0.550 |
| Non surgical |
11.3 |
23.1 |
0.028 |
| Urinary infection |
2.8 |
9.6 |
0.048 |
| Pneumonia |
3.8 |
6.7 |
0.371 |
| Cardiopulmonary events |
0.9 |
4.8 |
0.117 |
| Surgical |
50.0 |
31.7 |
0.018 |
| Wound infections (any grade) |
20.8 |
9.6 |
0.034 |
| Perineal wound infections (rectum exstirpation only) |
42.2 |
18.8 |
0.032 |
| Anastomosis leakage (LAR only) |
26.6 |
9.7 |
0.020 |
| Operative revision (LAR only) | 20.3 | 6.5 | 0.035 |
After administrating intensified neoadjuvant treatment, there is no increase in non surgical morbidity, but a severe increase in surgical morbidity like anastomosis leakage or wound infections.