Table I.

Data on 4-nitroquinoline 1-oxide (4-NQO)-induced oral and esophageal cancer development in mice.

Treatment groups	Number of mice	Initial body weight (g)	Final body weight (g)	Site	Number of animal affected	Number of dysplasia or tumor mass
Control	10	23.69 ± 1.902	33.63 ± 5.3	Tongue	0	0
				Esophagus	0	0
4-NQO
15 μg/ml	10	22.5 ± 1.211	32.23 ± 4.7	Tongue	1	1
				Esophagus	4	7
30 μg/ml	10	23.53 ± 1.271	26.14 ± 3.5	Tongue	7	14
				Esophagus	8	19
45 μg/ml	10	22.62 ± 1.651	23.97 ± 1.5	Tongue	9	19
				Esophagus	8	12