Figure 4. Male Pectoral Fin ET Undergo Vigorous Renewal.
(A) Section images of male dkk1b:EGFP pectoral fin ET at 1 hour, 1 day, 7 days, or 14 days after EdU injection. Arrows indicate EdU+dkk1b:EGFP-expressing cells. Green: EGFP immunofluorescence; red: EdU immunofluorescence; blue: DAPI.
(B) Whole-mount images of TCFsiam; dkk1b:EGFP pectoral fins. Males expressed both reporters in ET.
(C) Section image of a male TCFsiam; dkk1b:EGFP pectoral fin ET. Arrowheads indicate TCFsiam+ cells. Cuticle shows red autofluorescence in these images.
(D) Ubiquitous overexpression of dkk1b decreased the number of ET in male pectoral fins and reduced their definition. Data are shown as mean ± s.d., *P < 0.001 by two-tailed Student’s t-test.
Scale bars = 10 μm (A, C). See also Figure S3.