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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Pediatr Blood Cancer. 2013 Sep 4;61(1):10.1002/pbc.24697. doi: 10.1002/pbc.24697

Figure 3. Interaction of Olaparib and SN-38.

Figure 3

Growth inhibition (mean, SD) following exposure to 1µM olaparib (light grey), cell line specific concentration of SN-38 (black), or concomitant exposure to both agents (dark grey). Concentrations of SN-38, determined by the IC50 ratio of SN38 to olaparib, ranged from 0.00013 to 0.0033 µM and were the same in single agent and combination data presented.