Table 3.
Multivariate analysis of CT gene expression with MTHFR 677 genotypes
| Parameter | OR | 95% CI | P* | |
|---|---|---|---|---|
|
MTHFR 677 C>T (rs1801133) |
CC |
32.33 |
2.42-431.52 |
0.003 |
| CT/TT |
1** |
|
|
|
| Age$ |
|
1.03 |
0.94-1.12 |
0.69 |
|
Sex(female vs. male) |
|
0.28‡ |
0.02-3.86 |
0.52 |
|
Histology |
SQCC# |
18.46 |
1.19-284.49 |
0.04 |
| non-SQCC |
1** |
|
|
|
| T Stage | T1 |
0.31 |
0.03-3.56 |
0.53 |
| T2, 3, 4 | 1** | |||
* Computed from a logistic regression model using the EXACT option of PROC LOGISTIC in SAS to account for the small data set; $continuous variable. #SQCC Squamous cell carcinoma; ‡reference = male; **reference group.