Table 4.
Multivariate logistic regression modeling of association between 1-carbon enzyme alleles and CT gene expression
| Polymorphism | OR$ | 95% CI | P* |
|---|---|---|---|
|
MTHFR 677 (rs1801133) |
13.18 |
1.96-88.5 |
0.004 |
|
MTHFR 1298 (rs1801131) |
0.56 |
0.15-2.09 |
0.53 |
|
MTR 2756 (rs1805087) |
0.81 |
0.14-4.75 |
1 |
|
MTRR 66 (rs1801394) |
0.67 |
0.22-2.00 |
0.52 |
| RFC 80 (rs1051266) | 0.7 | 0.24-2.07 | 0.62 |
$ Based on number of major alleles, adjusted for age, sex, histology and t stage; * computed using the EXACT option of PROC LOGISTIC in SAS to account for the small data set.