Fig. 6.
Correlation between mitochondrial non-heme iron level and caspase-9 and caspase-3 activities. Pearson’s tests were performed to determine whether mitochondrial iron levels correlate with caspase-9 and caspase-3 activities. Iron levels in subsarcolemmal mitochondria (SSM) significantly correlated with (A) caspase-9 activity (n = 26) and (B) caspase-3 activity (n = 26). There was no correlation between interfibrillar mitochondria’s (IFM) iron contents and (C) caspase-9 activity, whereas a positive correlation between iron levels and (D) caspase-3 activity was found in IFM (n = 25).