Table 1.
Family | Mutation 1 | Mutation 2 | Mutation 3 |
KK021 | IVS3-2A→G | IVS3-2A→G | |
PB043 | A364E (BBS4) | A364E (BBS4) | T558I (BBS2)a |
AR153 | L327P | BBS1? | BBS1? |
AR708 | N165H | Unknown | Unknown |
AR717 | S457I | Unknown | Unknown |
Although three mutant alleles are listed, the affected individual (PB043-01) in family PB043 carries four potential mutations, since he is homozygous for both A364E and T558I.