Table 1.
Baseline characteristics of patients
| Characteristic | Intervention (n = 905) | Usual care (n = 927) |
|---|---|---|
| Male, n (%) |
575 (63.5) |
589 (63.5) |
| Mean age, years (SD) |
62.1 (7.9) |
62.4 (7.7) |
| Height, cm (SD) |
166.9 (9.3) |
167.4 (9.1) |
| Weight, kg (SD) |
85.8 (16.5) |
85.6 (15.9) |
| Body Mass Index, kg/m2 (SD) |
30.7 (5.2) |
30.5 (5.0) |
| Men with waist ≥ 102 cm, n (%) |
358 (62.8) |
385 (66.3) |
| Women with waist ≥ 88 cm, n (%) |
279 (85.6) |
278 (85.3) |
| Mean systolic blood pressure, mmHg (SD)a |
145.9 (15.3) |
138.7 (13.5) |
| Mean diastolic blood pressure, mmHg (SD)a |
83.7 (11.7) |
80.6 (9.2) |
| Heart rate, beats/min (SD) |
71.4 (10.9) |
71.6 (10.4) |
| Total cholesterol, mmol/l (SD) |
5.27 (1.15) |
5.29 (1.14) |
| HDL, mmol/L (SD) |
1.30 (0.35) |
1.32 (0.37) |
| LDL, mmol/L (SD) |
3.19 (1.02) |
3.21 (1.04) |
| Triglyceride, mmol/L (SD) |
1.84 (1.19) |
1.78 (1.00) |
| Creatininemia μmol/L (SD) |
86.2 (29.9) |
85.4 (25.5) |
| MDRD-estimated glomerular filtration rate, ml/min (SD) |
79.6 (19.6) |
80.8 (20.2) |
| Fasting glycemia, mmol/l (SD) |
6.88 (1.94) |
6.77 (1.94) |
| Left ventricular hypertrophy, n (%) |
150 (16.6) |
184 (19.9) |
| Family history of early cardiovascular event, n (%) |
225 (24.9) |
253 (27.3) |
| Albuminuria ≥ 20 mg/L, n (%) |
186 (22.3) |
154 (18.1) |
| Mean years since diagnosis of hypertension (SD) |
10.5 (7.8) |
11.2 (8.3) |
|
Smoker status |
|
|
| Current n (%) |
193 (21.3) |
217 (23.4) |
| Past smoker < three years n (%) |
72 (8.0) |
94 (10.2) |
| Non-smoker n (%) |
640 (70.7) |
615 (66.4) |
| Number of antihypertensive drugs, n (SD) |
2.16 (1.04) |
2.18 (1.04) |
| Type-2 diabetes, n (%) |
527 (58.2) |
521 (56.2) |
| Mean years since diagnosis of type-2 diabetes, (SD) |
6.9 (6.1) |
7.8 (6.9) |
| HbA1c, % (SD) |
7.0 (1.1) |
7.0 (1.2) |
| Cardiovascular risk factors, n (%) |
|
|
| Men > 50 or women > 60 years old |
779 (86.1) |
802 (86.6) |
| Current smoker or past smoker < three years |
265 (29.3) |
311 (33.6) |
| LDL ≥ 4.14 mmol/L or treatment |
692 (76.5) |
686 (74.0) |
| HDL ≤ 1.04 mmol/L |
189 (20.9) |
190 (20.6) |
| Number of cardiovascular risk factors, n (%) |
|
|
| ≤ 2 |
259 (28.6) |
264 (28.5) |
| 3 |
319 (35.2) |
315 (34.0) |
| 4 |
222 (24.5) |
247 (26.6) |
| ≥ 5 |
105 (11.6) |
101 (10.8) |
| Ten-year Framingham-Anderson risk score, (%) |
17.5 |
17.0 |
| Achieved all therapeutic targets (3 or 5), n/N (%)a |
56/900 (6.2) |
94/923 (10.2) |
| Achieved blood pressure target, n (%)a |
207 (23.0) |
392 (42.6) |
| Achieved LDL target, n (%) |
370 (41.1) |
395 (43.4) |
| No smoking, n (%) |
712 (78.7) |
709 (76.6) |
|
Patients with diabetes |
|
|
| Achieved HbA1c target n/N (%) |
312/527 (60.1) |
316/521 (61.7) |
| Low-dose aspirin (yes) n/N (%)a | 225/527 (42.7) | 140/521 (26.9) |
astatistically significantly different between groups (P < 0.001).
MDRD, modified diet in renal disease; SD, standard deviation.