Table 4.
Changes in the main clinical and biological parameters between month 0 and month 24
| Variable | Group | Month 0 Mean (SD) | Month 24 Mean (SD) | Estimated change over 24 months (SE) | Estimated difference ( P -value) |
|---|---|---|---|---|---|
| Systolic blood pressure (mmHg) |
Intervention (n = 905) |
145.9 (15.3) |
139.6 (14.6) |
-6.00 (0.46) |
-4.76 (< 0.001) |
| Usual care (n = 927) |
138.7 (13.5) |
137.2 (12.6) |
-1.24 (0.48) |
||
| Diastolic blood pressure (mmHg) |
Intervention (n = 905) |
83.7 (11.7) |
80.2 (10.4) |
-3.32 (0.38) |
-1.88 (< 0.001) |
| Usual care (n = 927) |
80.6 (9.2) |
79.2 (8.0) |
-1.44 (0.38) |
||
| LDL cholesterol (mmol/L) |
Intervention (n = 905) |
3.18 (1.03) |
2.82 (0.85) |
-0.31 (0.03) |
0.05 (0.075) |
| Usual care (n = 927) |
3.21 (1.03) |
2.92 (0.91) |
-0.26 (0.03) |
||
| MDRD-estimated GFR (ml/min) |
Intervention (n = 905) |
79.6 (19.6) |
80.6 (20.1) |
1.52 (0.48) |
2.72 (< 0.001) |
| Usual care (n = 927) |
80.8 (20.2) |
78.9 (20.5) |
-1.20 (0.48) |
||
| Framingham-Anderson Score (%) |
Intervention (n = 905) |
17.47 |
15.24 |
-2.23 |
0.06 (0.001) |
| Usual care (n = 927) |
17.00 |
15.81 |
-1.19 |
||
| Weight (kg) |
Intervention (n = 905) |
85.8 (16.5) |
85.5 (16.8) |
-0.28 (0.12) |
-0.12 (0.470) |
| Usual care (n = 927) |
85.6 (15.9) |
85.4 (16.1) |
-0.16 (0.12) |
||
| Waist circumference (cm) |
Intervention (n = 905) |
105.1 (12.8) |
104.9 (13.3) |
-0.08 (0.16) |
-0.24 (0.269) |
| Usual care (n = 927) |
105.1 (13.3) |
105.3 (13.8) |
0.16 (0.16) |
||
| HbA1c (%) |
Intervention (n = 527) |
7.01 (1.12) |
7.03 (1.10) |
0.03 (0.04) |
0.01 (0.341) |
| Usual care (n = 521) | 7.01 (1.23) | 7.03 (1.13) | 0.02 (0.04) |
LDL, low-density lipoprotein; MDRD-estimated GFR, MDRD-estimated glomerular filtration rate; SD, standard deviation; SE, standard error. P-values refer to the comparison of the changes between the intervention and usual care groups in a three-level hierarchical generalized linear model (see Statistics section).