Table 3.
Sequences and Ancestral States[Note]
|
Sequencea |
|||||
| Polymorphic Site (Location) | Human | Chimpanzee | Gorilla | Orangutan | Consensus AncestralState (Symbol) |
| ADH7 StyI (intron 5) |
G/C CATGG |
C CATGG |
C CATGG |
Unknown | Site present (2) |
| ADH1C: | |||||
| EcoRI (intron 2) | GAAT T/G C |
GAAT T C |
GAAT T C |
AAACT C |
Site presentb (2) |
| HaeIII (exon 5) |
A/G GCC |
A GCC |
A GCC |
A GCC |
Site absent (1) |
| Ile349Val | AAT A/G TT |
AAT G TT |
AAT G TT |
AAT G TT |
349Val (2) |
| ADH1B: | |||||
| Arg47His | C A/G CACAGATG |
C G CACAGATG |
C G CACAGATG |
C G CACAGATG |
47Arg (1) |
| RsaI (intron 3) | G T/C AC |
G C AC |
G C AC |
G C AC |
Site absent (1) |
| Arg369Cys | CAGTATC C/T G |
CAGTATC C G |
CAGTATC C G |
CAGTATC C G |
369Arg (1) |
Note.— SNP are indicated in boldface, and the sequence differences are italicized and underlined.
Oriented in the 5′→3′ direction in the gene cluster.
With the exception of orangutan, in which two different base changes result in the restriction site being absent.