Table 4.
Association of both standard and highly sensitive cardiac troponin I assays with an echo diagnosis of definite HCM, using logistic regression analysis
| Odds ratio (95% CI) | P value | Pseudo R2 | AUROC (95% CI) | ||
|---|---|---|---|---|---|
|
cTnI models | |||||
| Model 1* |
Natural log of cTnI |
4.20 (0.94, 18.80) |
0.060 |
0.102 |
0.66 (0.51, 0.82) |
| Model 2 ** |
2.56 (0.54, 12.14) |
0.236 |
0.197 |
0.76 (0.62, 0.91) |
|
|
hsTnI models | |||||
| Model 1* |
Natural log of hsTnI |
2.35 (1.39, 3.96) |
0.001 |
0.173 |
0.78 (0.65, 0.90) |
| Model 2 ** | 1.82 (1.02, 3.24) | 0.042 | 0.231 | 0.81 (0.70, 0.93) | |
* Model 1 adjusted for age and sex.
** Model 2 adjusted for age, sex, presence of group 2 ECG abnormalities, and symptoms of dyspnoea, chest pain, syncope or palpitations.
Footnote: For the ln(cTnI): comparison between AUROC in Model 1 vs Model 2: χ2=1.90, p=0.168. For the ln(hsTnI): comparison between AUROC in Model 1 vs Model 2: χ2=1.03, p=0.310. For the comparison between the AUROCs in Model 2 for the models with ln(cTnI) and ln(hsTnI): χ2= 0.87, p=0.351.