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. 2011 Jul 30;1(1):18–26. doi: 10.5681/apb.2011.003

Table 4. Comparision of various release characteristics of anhydrous theophylline from different microsphere formulations, physical mixture and teophylline SR® tablet.

Formulation aQ2 bQ8 ct
50%
(h) 		dDE Similarity
factor
F1 63.3±3.6 100.19±0.16 0.75 89.21 27.29
F2 65.3±0.3 99.11±0.19 0.5 95.08 20.07
F3 54.9±0.2 92.64±1.41 0.5 89.47 22.95
F4 50.6±0.5 94.52±0.23 2 88.39 24.63
f 48.5±3.2 92.80±1.85 2 91.28 27.32
PM 64.8±1.4 102.20±1.54 0.5 96.36 21.63
Theophylline
SR® 		12.8±1.5 80.86±5.74 5 73.94 100