Table 2.
Relationship of EPCAM expression with pathological parameters of tumor
|
Clinical parameters |
EPCAM |
|||
|---|---|---|---|---|
| Low | High | t/χ2/r | P | |
| Age(yrs) |
56.85 ± 11.4 |
61.51 ± 12.22 |
4.787 |
0.0001 |
| Gender |
|
|
0.805 |
0.370 |
| Male |
257 (60.0%) |
171 (40.0%) |
|
|
| Female |
97 (56.1%) |
76 (43.9%) |
|
|
| Location |
|
|
10.37 |
0.006 |
| Proximal |
37 (44.0%) |
47 (56.0%) |
|
|
| Middle |
130 (58.3%) |
93 (41.7%) |
|
|
| Distal |
187 (63.6%) |
107 (36.4%) |
|
|
| Size |
|
|
40.47 |
0.0001 |
| <5 cm |
244 (69.7%) |
106 (30.3%) |
|
|
| ≥5 cm |
110 (43.8%) |
141 (56.2%) |
|
|
| Lauren classification |
|
|
198.1 |
0.0001 |
| Intestinal |
261 (87.3%) |
38 (12.7%) |
|
|
| Diffuse |
93 (30.8%) |
209 (69.2%) |
|
|
| Histology |
|
|
3.136 |
0.371 |
| Papillary adenocarcinoma |
20 (69.0%) |
9 (31.0%) |
|
|
| Tubular adenocarcinoma |
254 (57.9%) |
185 (42.1%) |
|
|
| Mucinous adenocarcinoma |
19 (51.4%) |
18 (48.6%) |
|
|
| Signet-ring cell carcinoma |
61 (63.5%) |
35 (36.5%) |
|
|
| Histologic differentiation |
|
|
6.323 |
0.097 |
| Well |
12 (70.6%) |
5 (29.4%) |
|
|
| Moderately |
113 (64.6%) |
62 (35.4%) |
|
|
| Poorly |
227 (55.8%) |
180 (44.2%) |
|
|
| Others |
2 (100.0%) |
0 (0.0%) |
|
|
| Invasion depth |
|
|
107.1 |
0.0001 |
| T1 |
73 (91.2%) |
7 (8.8%) |
|
|
| T2 |
113 (80.1%) |
28 (19.9%) |
|
|
| T3 |
160 (47.3%) |
178 (52.7%) |
|
|
| T4 |
8 (19.0%) |
34 (81.0%) |
|
|
| TNM stages |
|
|
201.6 |
0.0001 |
| I |
119 (93.7%) |
8 (6.3%) |
|
|
| II |
116 (85.9%) |
19 (14.1%) |
|
|
| III |
99 (42.9%) |
132 (57.1%) |
|
|
| IV |
20 (18.5%) |
88 (81.5%) |
|
|
| Lymphatic metastasis |
|
|
119.1 |
0.0001 |
| No |
193 (87.7%) |
27 (12.3%) |
|
|
| Yes |
161 (42.3%) |
220 (57.5%) |
|
|
| Regional lymph nodes |
|
|
182.6 |
0.0001 |
| PN0 |
193 (87.7%) |
27 (12.3%) |
|
|
| PN1 |
118 (59.6%) |
80 (40.4%) |
|
|
| PN2 |
42 (31.1%) |
93 (68.9%) |
|
|
| PN3 |
1 (2.1%) |
47 (97.9%) |
|
|
| Distant metastasis |
|
|
53.42 |
0.0001 |
| No |
332 (65.1%) |
178 (34.9%) |
|
|
| Yes | 22 (24.2%) | 69 (75.8%) | ||