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+ and – denote capacity and incapacity of hydroxylation. The conversion of substrates (%) is given in parentheses.
| Substrate | CYP71D351 | CYP71D12 |
|---|---|---|
| Naringenin | – | – |
| Tryptamine | – | – |
| Secologanin | – | – |
| Strictosidine | – | – |
| Ajmalicine | – | – |
| Tabersonine | +++ (96.3 ± 0.6) | +++ (93.6 ± 0.3) |
| 2.3-Dihydrotabersonine | + (31.3 ± 1.7) | +/− (2.1 ± 0.2) |
| 2.3-Dihydro-3-hydroxytabersonine | + (18.2 ± 0.9) | +/− (2.6 ± 0.2) |
| Vindoline | – | – |
| Catharanthine | – | – |
