Trunk and limb skeletal defects from the TGFβ2-null mice. (A) Forelimbs from E18.5 wild-type (top) and null (lower) siblings showing missing deltoid tuberosity (dt), reduced olecranon process (op) and shortened radius and ulna in null limb. Bar, 2.7 mm. (B) Hindlimbs from E18.5 wild-type (top) and null (lower) siblings showing extended foot and absent third trochanter (tt) in the mutant limb. Bar, 2.7 mm. (C) Spinal column from wild-type E18.5 mouse showing normal neural arches from a dorsal-lateral aspect. Bar, 1.4 mm. (D) Spinal column from E18.5 null sibling mouse showing the neural arch defect (nad) from a dorsal-lateral aspect. Bar, 1.4 mm. (E) Ventral rib cage from a wild-type E18.5 mouse. Bar, 2.2 mm. (F) Ventral rib cage from a null sibling E18.5 mouse showing a bifurcated sternum. Bar, 2.2 mm. (G) Clavicles from E18.5 wild-type (top) and null (lower) siblings showing ventral curvature of the null clavicle. Bar, 0.9 mm.