Table 3.
Multivariable-adjusted geometric mean (95% confidence interval) serum concentrationsa of sex steroid hormones and SHBG by race/ethnicity in 134 adolescent males, NHANES III (Phase I), 1988–1991
| 12–15 year olds (N = 57) |
16–19 year olds (N = 77) |
|||||
|---|---|---|---|---|---|---|
| Pairwise Comparisons |
Pairwise Comparison |
|||||
| Hormone | Mean (95% CI) | versus Non- Hispanic white |
versus Non- Hispanic black |
Mean (95% CI) | versus Non- Hispanic white |
versus Non- Hispanic black |
| Testosterone (ng/mL) | ||||||
| Non-Hispanic white | 2.14 (1.78, 2.57) | -- | -- | 4.79 (4.01, 5.72) | -- | -- |
| Non-Hispanic black | 1.32 (0.86, 2.02) | 0.043 | -- | 5.54 (4.95, 6.21) | 0.23 | -- |
| Mexican-American | 3.04 (1.96, 4.73) | 0.14 | 0.002 | 6.07 (5.33, 6.91) | 0.080 | 0.23 |
| Free Testosterone (ng/mL) | ||||||
| Non-Hispanic white | 0.030 (0.024, 0.038) | -- | -- | 0.110 (0.090, 0.133) | -- | -- |
| Non-Hispanic black | 0.017 (0.011, 0.026) | 0.030 | -- | 0.126 (0.111, 0.144) | 0.28 | -- |
| Mexican-American | 0.038 (0.026, 0.055) | 0.29 | 0.005 | 0.143 (0.122, 0.167) | 0.080 | 0.17 |
| Estradiol (pg/mL) | ||||||
| Non-Hispanic white | 24.81 (23.04, 26.72) | -- | -- | 35.81 (31.80, 40.33) | -- | -- |
| Non-Hispanic black | 20.52 (16.99, 24.79) | 0.11 | -- | 36.61 (32.71, 40.96) | 0.83 | -- |
| Mexican-American | 20.27 (17.27, 23.78) | 0.033 | 0.92 | 34.00 (31.21, 37.05) | 0.57 | 0.23 |
| Free Estradiol (pg/mL) | ||||||
| Non-Hispanic white | 0.515 (0.466, 0.570) | -- | -- | 0.975 (0.856, 1.111) | -- | -- |
| Non-Hispanic black | 0.471 (0.367, 0.603) | 0.56 | -- | 0.951 (0.852, 1.061) | 0.82 | -- |
| Mexican-American | 0.473 (0.383, 0.585) | 0.48 | 0.97 | 0.855 (0.780, 0.937) | 0.20 | 0.060 |
| SHBG (nmol/L) | ||||||
| Non-Hispanic white | 56.45 (49.78, 64.00) | -- | -- | 24.10 (21.26, 27.32) | -- | -- |
| Non-Hispanic black | 53.49 (43.29, 66.10) | 0.73 | -- | 25.94 (21.34, 31.54) | 0.56 | -- |
| Mexican-American | 37.77 (29.86, 47.76) | 0.010 | 0.047 | 26.14 (22.76, 30.02) | 0.43 | 0.94 |
a
Geometric mean adjusted for age, Tanner stage, percent body fat, waist circumference, frequency of physical activity, cotinine (as an indicator of tobacco smoke exposure), and mutually for the other hormones (total testosterone, total estradiol, and SHBG in one model; free testosterone and free estradiol in another model).