Figure 7. Replication kinetics of the chimeric viruses derived from the molecular clones pXJDC13(2-7V1V2) and pXJDC2-7(13V1V2), in comparison with parental clones pXJDC13 and pXJDC2-7. 3×10⁶ PHA-stimulated PBMCs were infected with viruses normalized at 400 TCID₅₀ in triplicate.

Virus production was monitored by measuring HIV-1 p24 antigen concentration in culture supernatant every 3–4 days. The results shown are the mean value with standard deviations from three independent experiments.