Skip to main content
. Author manuscript; available in PMC: 2014 May 10.
Published in final edited form as: Circ Res. 2013 Mar 26;112(10):10.1161/CIRCRESAHA.113.301055. doi: 10.1161/CIRCRESAHA.113.301055

Fig. 4.

Fig. 4

Regional accumulation of dephosphorylated Cx43 isoform P0 in TnT-I79N after pacing. This is not observed in TnT-WT, in TnT-I79N before pacing and is prevented by BLEB. Anti-Cx43 (green) and anti-Cx43-P0 (red) staining of I79N heart sections before (A) and after pacing (B, two examples are shown for I79N after pacing). The scale bar length is 100 μm. (C) Summary data for integrated density (mean intensity x area (pixel)) of Cx43 (N numbers are indicated in columns and are the same for both graphs). See Supplemental Fig. III for examples of anti-Cx43 staining (green) only for all groups. (D) Summary data for the average ratio of Cx43/Cx43-P0 in all groups (C) * p≤0.05