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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: J Clin Immunol. 2012 Oct 18;33(2):10.1007/s10875-012-9817-6. doi: 10.1007/s10875-012-9817-6

Fig. 1. Patients with sarcoidosis have a greater frequency of Th-17 cells in the peripheral blood compared to healthy controls.

Fig. 1

a Analysis of the mRNA expression of the master transcription factor retinoic acid-related orphan receptor RORγt from CD4+ T cells isolated from the peripheral blood of healthy controls, (n=6) and sarcoidosis patients (n=10). b CBA analysis of IL-17A production from polyclonally activated CD4+ T cells isolated from the peripheral blood of healthy controls (diamonds, n=11) and patients with sarcoidosis (squares, n=28). c Representative plots of flow cytometric detection of intracellular IL-17A and surface expression of IL-23R on CD4+ T cells from polyclonally activated PBMC. d Frequencies of IL-17A+CD4+ and IL-23R+CD4+ from polyclonally activated PBMC of healthy controls (diamonds, n=11) and patients with sarcoidosis (square, n=25). P values are indicated